Well my mother just recently went in for her first biopsy on a lump the doctor found in her right breast. It was about the size of a quarter. It was an out patient procedure where they numbed the area and stuck a needle half the size around as a pencil in and removed the tissue for testing. When the doctor took the first sample, a large portion was removed so when he began to take another sample he removed the rest of the mass. The doctor believes that he got all the mass and now we are waiting to hear on the sample. Hopefully it is benign and not malignant at all. If it is malignant then my mother will have to have chemotherapy. When they do a biopsy they also put a metal marker in the area of the mass to mark where there was a mass. If another mass shows up later in the same spot then it is very likely the mass was not all removed, if a mass forms in another area then it has probably spread or there is another cluster of cancer starting.