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Monkey Butter's blog: "Breast Cancer"

created on 10/03/2007  |  http://fubar.com/breast-cancer/b137174
http://www.breastcancerhealth.org/webcast_transcript.asp?b=breastcancerhealth&f=breast_cancer&c=breast_anthracycline Anthracyclines for Breast Cancer: Does Stage Matter? Summary & Participants Anthracycline-based therapy is a popular approach for the treatment of breast cancer in both early and advanced stages. Studies have shown that it can effectively prevent recurrence while preserving the patients quality of life. Tune is as doctors from the 24th Annual San Antonio Breast Cancer Symposium share their thoughts about anthracyclines and the role they play in the different disease stages. Host: Cathy Conley KLRU-TV, Austin, Texas (PBS) Participants: Hyman B. Muss, MD Associate Director for Cancer Research, Vermont Cancer Center Hope S. Rugo, MD Medical Oncologist and Hematologist Associate Clinical Professor of Medicine, UCSF Webcast Transcript CATHY CONLEY: Hi, I'm Cathy Conley, and I'm here at the 24th Annual San Antonio Breast Cancer Symposium, where experts meet every year to share new data and discuss the latest strategies to fight breast cancer. I met with some experts to discuss anthracyclines and the role they play in early and advanced stage breast cancer. Doctor, breast cancer is a very diverse disease. Can you review the main stages? HOPE RUGO, MD: Stage I is small cancer that is confined to the breast, and it hasn't spread through the lymph circulation or blood circulation to the nodes under the arm. Those lymph nodes are where the blood flow and lymph flow go to apparently first from the breast. Stage II breast cancer, that's when either the tumor is a little bit larger, or it's also spread to nodes under the arm. Stage III breast cancer is a little more advanced. These are larger tumors, probably larger than a small apple, and in that situation, sometimes the tumor is large enough or growing fast enough that there's redness over the surface of the breast, or the tumor actually has invaded in the skin of the breast, and that's called stage III, or inflammatory breast cancer. Stage IV breast cancer is a very heterogeneous disease. This is breast cancer that has spread outside of the breast and the draining lymph nodes under the arm to somewhere else in the body. The cancer spreads, again, by the bloodstream or by the lymph circulation to the lungs, the liver, bone, sometimes the lymph nodes in other parts of the body, sometimes even the brain. The stages are really divided I through III, and IV into disease that is potentially curable and disease which we consider incurable. So much of what we understand and use for decisions about treatment have to do with what stage you are and what we understand the curability to be. CATHY CONLEY: So how does the treatment approach differ from early stage disease and metastatic disease? HOPE RUGO, MD: Metastatic breast cancer, or stage IV breast cancer, where breast cancer cells -- they look just like the breast, cancer cells that are from breast tissue -- are in other organs, like liver, lung or bone. In that situation, we currently don't appear to be curing that disease. That doesn't mean that we can't help people to live longer and have better quality of life. So our goal needs to be very clear for metastatic, advanced stage, stage IV breast cancer -- all those terms are used -- that what we're doing is preserving quality of life and quantity of life. Page 1 of 3 Next Page >> To learn more about similar topics, please visit our Breast Cancer section.
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